Henry Völzke

The paper identifies 16 genetic loci interacting with sleep duration to influence glycemic traits in over 480,000 individuals, revealing distinct biological mechanisms for short and long sleep.

The paper examines how polygenic indices for educational attainment change across birth cohorts and regions in Germany, finding stronger associations in recent cohorts and the East but weaker effects for women.

This study uses MRI scans to detect accelerated ageing patterns in specific organs and their associations with diseases and lifestyle factors.

The paper identifies contmeQTLs linking childhood adversity to epigenetic changes in immune cells, which are associated with disease risk and inflammatory profiles.

This study identifies 14 susceptibility loci for Ewing sarcoma through a genome-wide association meta-analysis, revealing genetic interactions with somatic EWSR1::FLI1 fusions.

This study identifies a shared genetic factor underlying brain age gaps across 30 cohorts, finding 19 SNPs and associations with health traits.

This study identifies lifestyle, early-life, and genetic factors associated with brain age gaps in individuals with major depressive disorder compared to controls.

This study identifies 67 genetic loci associated with head size, finding strong overlaps with cancer pathways and genes, suggesting shared genetic mechanisms between head growth and cancer risk.

This study identifies genetic variants associated with income and shows they correlate with health outcomes and educational attainment.

This study investigates the genetic and environmental factors influencing head motion during MRI, finding no significant single variants and no mediation by physiological or psychological factors.

This study performs a genome-wide association analysis of hemorrhoidal disease in 944,133 individuals, identifying 102 risk loci and linking them to vascular and tissue development pathways.

The paper identifies 31 host genetic loci influencing gut microbiome composition through GWAS and suggests causal effects in inflammatory diseases.

This study identifies new genetic loci associated with myocardial infarction and coronary heart disease using genome-wide association analyses across multiple cohorts.

This study identifies 5,552 blood-cell trait-variant associations across 746,667 individuals from 5 global populations, including 71 novel loci and ancestry-specific variants not found in European ancestry populations.

This study identifies 5,106 new genetic variants associated with blood cell traits using large-scale GWAS, highlighting the polygenic and monogenic basis of hematopoiesis.

The paper identifies SNPs with sex-specific effects on lung function traits using UK Biobank data, finding a significant interaction at rs7697189 near HHIP.

This paper examines brain aging in major depressive disorder (MDD) using a large dataset, finding that MDD patients show increased brain age differences compared to controls.

This study identifies subcortical shape differences in MDD patients using ENIGMA data, highlighting region-specific changes in surface area and thickness.

The paper harmonizes 10,232 structural brain MRIs from 18 studies to create a normative reference of brain development and aging across 3 to 96 years.

This paper conducts a GWAS on suicide attempt across psychiatric disorders, identifying genetic loci and showing polygenic risk for major depression predicts suicide attempt in multiple disorders.

This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.

This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.