Author

Gal Bitan

University of California, Los AngelesORCID 0000-0001-7046-3754Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra SilvaiD· 1 shared Ana Luı́sa CarvalhoiD· 1 shared Andreia Neves‐CarvalhoiD· 1 shared Andreia Teixeira‐CastroiD· 1 shared Annalisa PastoreiD· 1 shared Beatriz Rocha Ilidio RodriguesiD· 1 shared Carter LantziD· 1 shared Chioko NagaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Alexandra SilvaORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedJul 15, 2026

Development of an RNA Aptamer as a Therapeutic Agent for Synucleinopathies

Kazuma Murakami, Thi Hong Van Nguyen, Leo Tsuda…·Gal Bitan

This paper develops an RNA aptamer, 1R6, that targets synuclein and shows therapeutic potential in synucleinopathies by inhibiting aggregation and promoting disaggregation.

DOI 10.1038/s41467-026-75209-z

Drosophilaexperimental assay

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BiophysicsAdvanced SciencePeer-reviewedNov 26, 2025

Allosteric Modulation of Pathological Ataxin-3 Aggregation: A Path to Spinocerebellar Ataxia Type-3 Therapies

Alexandra Silva, Sara Duarte‐Silva, Pedro Miguel Martins…·Sandra Macedo‐Ribeiro

This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.

DOI 10.1002/advs.202502216

humanC. elegans

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