Sašo Čemerski

The paper shows that TCR and IL2 receptor signaling synergize at the immunological synapse of CD8+ T cells, enhancing T-T synapse formation and function.

This paper develops a low-matrix co-culture platform to evaluate T cell engager activity in patient-derived CRC organoids, showing dose-dependent cytotoxicity and immune activation across diverse models.

This study shows PD-1 blockade enhances T cell activation by altering ligand interactions between CD28, CTLA4, and PD-1, leading to stronger CD28-CD80 co-stimulation.