Author

Vinh Au

AstraZeneca (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Andrew Garcia· 1 shared Anna Kolobova· 1 shared Cailian LiiD· 1 shared Daniel AkumaiD· 1 shared Gee Sung EuniD· 1 shared Gongliang ZhangiD· 1 shared Gregory V. CarriD· 1 shared Helen L. Rowley· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Andrew Garcia

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PD-1 blockade enhances T cell activation by reorchestrating CD28 and CTLA4 ligand interactions

Gee Sung Eun, Jonathan Boyd, Vinh Au, Andrew Garcia, Sašo Čemerski, Simon J. Dovedi, Kristen N. Pollizzi, Michael Loran Dustin, Rajat Varma

This study shows PD-1 blockade enhances T cell activation by altering ligand interactions between CD28, CTLA4, and PD-1, leading to stronger CD28-CD80 co-stimulation.

bioRxiv · Apr 15, 2026 · PreprintImmunology

Novel, non-nitrocatechol COMT inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

Spencer Byers, Ingrid P. Buchler, Michael J. Depasquale, Helen L. Rowley, Rajiv S. Kulkarni, Lucy Pinder, Anna Kolobova, Cailian Li, Vinh Au, Daniel Akuma, Gongliang Zhang, Huijun Wei, Sharon C. Cheetham, James C. Barrow, Gregory V. Carr

The paper identifies novel COMT inhibitors that improve cognitive flexibility in rats by modulating dopamine metabolites in the frontal cortex and cerebrospinal fluid.

Psychopharmacology · May 30, 2020Peer-reviewedNeuroscience