Jayson J. Smith

The paper identifies both cell-autonomous and non-cell-autonomous roles of UNC-3 in C. elegans motor neurons, revealing its impact on neuronal identity and downstream connectivity.

The paper creates a molecular atlas of adult C. elegans motor neurons, identifying 29 subclasses defined by transcription factor and neuropeptide codes, and shows conservation between C. elegans and mice.

This study identifies CFI-1 as a key regulator of neuronal terminal differentiation in C. elegans, revealing context-dependent activation and repression mechanisms in different neuron types.

The paper shows that Hox proteins maintain neurotransmitter identity in C. elegans motor neurons through a homeostatic mechanism involving a positive feedforward loop and negative feedback.

The paper describes a mounting protocol for live imaging of C. elegans larvae and adults using light sheet fluorescence microscopy.

The paper investigates the role of homeobox genes in neuronal identity specification in C. elegans, finding that 111 of 118 neuron classes require homeobox genes for proper differentiation.

The paper shows that BAF and PBAF SWI/SNF complexes differentially regulate cell cycle arrest and invasion in C. elegans anchor cells.

The paper introduces a CDK sensor to distinguish cycling cells from terminally differentiated cells in C. elegans and zebrafish, revealing commitment points and stochasticity in cell cycle control.

The paper identifies a gene regulatory network in C. elegans anchor cell invasion, showing how transcription factors function differently before and after specification.