Author

Adi Danieli‐Mackay

Universitätsmedizin GöttingenORCID 0000-0001-7337-3797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 1 Assay:scRNA-seq· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Argyris PapantonisiD· 4 shared Anne Zirkel· 2 shared Ioanna Papadionysiou· 2 shared Nataša JosipovićiD· 2 shared Andreas BeyeriD· 1 shared Antonios PapadakisiD· 1 shared Aoife O’ConnelliD· 1 shared Athanasia StavropoulouiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Argyris PapantonisORCID

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4 papers

Recent·Most cited

A single-cell strategy for the identification of intronic variants related to mis-splicing in pancreatic cancer

Emre Taylan Duman, Maren Sitte, Karly Conrads, Adi Danieli‐Mackay, Fabian Ludewig, Philipp Ströbel, Volker Ellenrieder, Elisabeth Heßmann, Argyris Papantonis, Gabriela Salinas

The paper develops a single-nucleus full-length RNA-sequencing approach to identify intronic variants linked to mis-splicing in pancreatic cancer.

NAR Genomics and Bioinformatics · Apr 4, 2024Peer-reviewedGenomics

Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor

Spiros Palikyras, Konstantinos Sofiadis, Athanasia Stavropoulou, Adi Danieli‐Mackay, Vassiliki Varamogianni‐Mamatsi, David Hörl, Simona Nasiscionyte, Yajie Zhu, Ioanna Papadionysiou, Antonios Papadakis, Nataša Josipović, Anne Zirkel, Aoife O’Connell, Gary Loughran, James Keane, , Argyris Papantonis

This study uses a small molecule inhibitor to rapidly and synchronously induce senescence-like features in human cells, enabling analysis of its core regulatory program without paracrine effects.

Aging Cell · Jan 9, 2024Peer-reviewedGenomics

Extreme structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs

Ting Xie, Adi Danieli‐Mackay, Mariachiara Buccarelli, Mariano Barbieri, Ioanna Papadionysiou, Quintino Giorgio D’Alessandris, Nadine Übelmesser, Omkar Suhas Vinchure, Liverana Lauretti, Giorgio Fotia, Xiaotao Wang, Lucia Ricci‐Vitiani, Jay Gopalakrishnan, Roberto Pallini M. D, Argyris Papantonis

The paper maps structural variants and neoloops in glioblastoma stem cells to show how they sustain tumor-specific transcriptional programs and identify patient-specific vulnerabilities.

bioRxiv · Apr 20, 2023 · PreprintGenomics

circRAB3IP modulates cell proliferation by reorganizing gene expression and mRNA processing in a paracrine manner

Nataša Josipović, Karoline Kragh Ebbesen, Anne Zirkel, Adi Danieli‐Mackay, Christoph Dieterich, Leo Kurian, Thomas B. Hansen, Argyris Papantonis

The paper identifies circRAB3IP as a circRNA that modulates cell proliferation by altering gene expression and mRNA processing through interactions with SF3B1 in a paracrine manner.

RNA · Aug 16, 2022Peer-reviewedGenomics