Author

Antonios Papadakis

University of CologneORCID 0000-0002-2416-6772Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Andreas BeyeriD· 3 shared Anne Zirkel· 2 shared Argyris PapantonisiD· 2 shared Isabell BrusiusiD· 2 shared Konstantinos Sofiadis· 2 shared Nataša JosipovićiD· 2 shared Adam AntebiiD· 1 shared Adi Danieli‐MackayiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Andreas BeyerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rare genetic variants in the IIS/mTOR signalling pathway identified in exceptionally long-lived individuals show shared in vitro effects associated with lifespan across species

Mara Neuerburg, Larissa Smulders, Erik B. van den Akker, Daniel Kolbe, Filippo Artoni, Isabell Brusius, Helena M. Hinterding, Laura Beltrame, Ramona Pahl, H. Eka D. Suchiman, Antonios Papadakis, Andreas Beyer, Marian Beekman, Almut Nebel, P. Eline Slagboom, , Joris Deelen

This study identifies rare genetic variants in the IIS/mTOR pathway in long-lived humans and shows they have shared functional effects on lifespan-related traits in mice.

bioRxiv · May 28, 2026 · PreprintGenetics

Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor

Spiros Palikyras, Konstantinos Sofiadis, Athanasia Stavropoulou, Adi Danieli‐Mackay, Vassiliki Varamogianni‐Mamatsi, David Hörl, Simona Nasiscionyte, Yajie Zhu, Ioanna Papadionysiou, Antonios Papadakis, Nataša Josipović, Anne Zirkel, Aoife O’Connell, Gary Loughran, James Keane, , Argyris Papantonis

This study uses a small molecule inhibitor to rapidly and synchronously induce senescence-like features in human cells, enabling analysis of its core regulatory program without paracrine effects.

Aging Cell · Jan 9, 2024Peer-reviewedGenomics

Aging-associated changes in transcriptional elongation influence metazoan longevity.

Cédric Debès, Antonios Papadakis, Sebastian Grönke, Özlem Karalay, Luke Stephen Tain, Athanasia Mizi, Shuhei Nakamura, Oliver Hahn, Carina Marianne Weigelt, Nataša Josipović, Anne Zirkel, Isabell Brusius, Konstantinos Sofiadis, Mantha Lamprousi, Yuxuan Lu, , Andreas Beyer

This study identifies aging-associated increases in transcriptional elongation speed across multiple species and shows that reducing this speed extends lifespan.

bioRxiv · Dec 5, 2022 · PreprintGenomics