Delphine Naquin

Tiarins, a diverse family of natural Trojan-horse aminoacyl-tRNA synthetase inhibitors discovered by genome mining

The paper identifies TFX as an antibiotic that inhibits arginyl-tRNA synthetase by acting as a Trojan-horse molecule, revealing it belongs to a broader family of natural inhibitors targeting various tRNA synthetases.

Drosophila Sociality Influences Immune Peptide Load and Apoptosis-induced Tumor Suppression independently of the Antitumor Peptide Defensin

The paper shows that Drosophila social context affects immune peptide levels and tumor suppression, independent of Defensin's role.

High-resolution HIV-1 m6A epitranscriptome reveals isoform-dependent methylation clusters and unique 2-LTR transcript modifications

The paper identifies 18 m6A sites in HIV-1 using Nanopore sequencing and reveals isoform-dependent methylation clusters and unique 2-LTR transcript modifications.

A bifunctional snoRNA with separable activities in guiding rRNA 2'-O-methylation and scaffolding gametogenesis effectors

The paper identifies a bifunctional snoRNA, snR107, that guides rRNA modification and scaffolds gametogenesis effectors in fission yeast.

A single domain intrabody as a novel tool to bias the subcellular trafficking of the follicle-stimulating hormone receptor

The paper describes a single domain intrabody, iPRC2, that biases the subcellular trafficking of the follicle-stimulating hormone receptor (FSHR) by rerouting it to early endosomes, reducing its surface recycling and cAMP production.

Single cell RNA-sequencing identifies the gene expression profile of the asexual and sexual invasive merozoites of the human malaria parasite

This study uses scRNA-seq to identify gene expression profiles of asexual and sexual merozoites in Plasmodium falciparum, revealing key genes involved in invasion and sexual commitment.