Cody L. Call

The paper introduces a CRISPR-Cas13d-based system for cell-specific mRNA knockdown in zebrafish, validated across CNS glia types, showing efficient target mRNA depletion and reproducible phenotypes.

This study shows that PIEZO1 and PIEZO2 channels in oligodendrocytes regulate sheath formation, expansion, and myelination by detecting mechanical cues.

This study identifies ADGRG1 as a key regulator of pre-myelinating oligodendrocyte development and axon ensheathment, showing its role in CNS myelin formation through RhoA activation.

This study investigates the role of P/Q-type voltage-gated calcium channels in oligodendrocyte lineage cells during myelination in zebrafish, finding that these channels are essential for normal myelination and calcium signaling.

This study shows that activating CB1 receptors in zebrafish leads to increased non-axonal ensheathment without affecting OL differentiation or normal myelin formation.

The paper identifies a conserved myelination mechanism in oligodendrocytes that forms paranodal bridges, enabling extended myelin sheaths along axons, which degenerate more frequently with age.

This paper introduces an automated cell tracking pipeline, Oligo-Track, to analyze oligodendrocyte dynamics in vivo, revealing suppressed oligodendrogenesis in deeper cortical layers after demyelination.

This study shows that remyelination restores myelin content on distinct neuronal subtypes in the cerebral cortex, preserving relative differences in myelin content despite changes in distribution.

This study uses in vivo imaging to show that remyelination after oligodendrocyte ablation in mice leads to altered myelin patterns in the cerebral cortex, with impaired regeneration in deeper layers.