Joseph A. Baur

This study shows that impaired glycolysis in bone tissue of aged mice leads to reduced bone formation, and that enhancing glycolysis can improve bone mass.

This study identifies tyrosine phosphorylation and dimerization as cooperative mechanisms activating NAMPT, enhancing NAD+ synthesis and cancer cell growth.

This study identifies coenzyme Q redox balance as a regulator of dopaminergic neuron activity and juvenile sleep in Drosophila by linking mitochondrial complex I function to sleep fragmentation and depth.

This study uses continuous glucose monitoring and indirect calorimetry in mice to assess metabolic responses to various physiological stressors, revealing dynamic changes in glycemia and energy expenditure.

This study develops a multi-nutrient differential equation model to show how competitive catabolism between glucose, fatty acids, and ketones under fasting conditions leads to systemic metabolic homeostasis, with implications for obesity-induced diabetes.

This paper investigates the role of PPP1R3B in hepatic metabolism, finding it acts as a switch that promotes glycogen storage over lipid accumulation, with implications for metabolic diseases.

This study shows that long-term NMN treatment improves healthspan and extends lifespan in female mice but not males, with sex-specific effects on metabolism and microbiome.

This study quantifies metabolic fluxes of circulating metabolites in mice using isotope tracing and mass spectrometry to identify major metabolic cycles and their tissue-specific contributions.