Author

Luísa Vaqueiro Lopes

University of LisbonORCID 0000-0001-8367-3005Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 6 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Assay:electronic health records· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

Joana Esteves CoelhoiD· 4 shared Mariana Temido‐FerreiraiD· 3 shared Miguel RemondesiD· 3 shared Aurore RiberaiD· 2 shared Inês Marques-MorgadoiD· 2 shared Joana Gomes-Ribeiro· 2 shared Paula A. PousinhaiD· 2 shared Ana ChegãoiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersNeuroscience

Joana Esteves CoelhoORCID

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Reinforced Hippocampus-Accumbens pathway marks a shift towards cognitive decline in aging

Aurore Ribera, Brenda Fernandes-Dias, Larissa Yugay, Emma Deneuville, Manuel Dias‐Silva, Marion Violain, Thibault Bouet, Ingrid Bethus, Luísa Vaqueiro Lopes, Peter Vanhoutte, Stephen Ramanoël, Jacques Barik, Paula A. Pousinha

The paper identifies age-related changes in the hippocampus-accumbens pathway in mice and links them to cognitive decline, showing that reducing pathway excitability can improve memory.

bioRxiv · Jan 22, 2026 · PreprintNeuroscience

Chronic Circadian Disturbance Reshapes Hippocampal Connectivity and Cognitive Function

Inês Marques-Morgado, Marcelo Dias, Joana Esteves Coelho, Carolina S. Peixoto, Mariana Temido‐Ferreira, Joana Gomes-Ribeiro, Miguel Remondes, Neil Dawson, Luísa Vaqueiro Lopes

This study identifies direct SCN-hippocampal projections and shows chronic circadian disruption causes memory impairment through network desynchronization.

bioRxiv · Dec 27, 2025 · PreprintNeuroscience

Auditory Gamma-Frequency Entrainment Abolishes Working Memory Deficits in a Rodent Model of Autism

Jorge Cardoso, Marta Luis, Catarina Mesquita, Luísa Vaqueiro Lopes, Miguel Remondes

This study shows that gamma-frequency auditory stimulation improves working memory deficits in a rodent autism model by enhancing neural oscillations.

bioRxiv · Jun 12, 2025 · PreprintNeuroscience

Mapping functional traces of opioid memories in the rat brain

Joana Gomes-Ribeiro, João Martins, José Sereno, Samuel Deslauriers‐Gauthier, Teresa Summavielle, Joana Esteves Coelho, Miguel Remondes, Miguel S. Castelo-Branco, Luísa Vaqueiro Lopes

This study identifies brain circuits involved in opioid memory formation and relapse by analyzing functional connectivity in rats during drug-context associations.

Brain Communications · Jan 1, 2024Peer-reviewedNeuroscience

Age-dependent NMDA receptor function is regulated by the Amyloid Precursor Protein

Joana Rajão‐Saraiva, Jade Dunot, Aurore Ribera, Mariana Temido‐Ferreira, Joana Esteves Coelho, Svenja König, Sébastien Moréno, Francisco J. Enguita, Michael Willem, Stefan Kins, Hélène Marie, Luísa Vaqueiro Lopes, Paula A. Pousinha

This study identifies APP's role in regulating NMDAR function during development and aging, showing distinct mechanisms in postnatal and aged stages.

Aging Cell · Jan 26, 2023Peer-reviewedNeuroscience

Glycation modulates glutamatergic signalling and exacerbates Parkinson's disease-like phenotypes

Ana Chegão, Mariana Guarda, Bruno M. Alexandre, Liana Shvachiy, Mariana Temido‐Ferreira, Inês Marques-Morgado, Bárbara Fernandes Gomes, Rune Matthiesen, Luísa Vaqueiro Lopes, Pedro R. Florindo, Ricardo A. Gomes, Patrícia Gomes‐Alves, Joana Esteves Coelho, Tiago F. Outeiro, Hugo Vicente Miranda

This study shows that glycation worsens Parkinson's-like symptoms in mice by enhancing glutamatergic signaling and causing dopaminergic neuron loss.

bioRxiv · Aug 24, 2021 · PreprintNeuroscience

Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice

David V.C. Brito, Kübra Gülmez Karaca, Janina Kupke, Franziska Mudlaff, Benjamin Zeuch, Rui Gomes, Luísa Vaqueiro Lopes, Ana M.M. Oliveira

This study shows that increased Gadd45γ expression in the hippocampus of aged humans and young adult mice impairs spatial memory and disrupts CREB signaling and activity-regulated genes.

Neurobiology of Aging · Jul 3, 2020Peer-reviewedNeuroscience