Block of Thalamic 5-HT2A Receptors modulates Tonic GABA-A Inhibition but not Absence Seizures
Anna Cavaccini, Marcello Venzi, Vincenzo Crunelli, Giuseppe Di Giovanni
The paper investigates the role of 5-HT2A receptor signaling in modulating tonic GABA-A inhibition and absence seizures in GAERS rats, finding that while it affects tonic currents, it does not alter seizure occurrence.