Margarida Barroso

Iron-endoplasmic reticulum-extracellular matrix axis regulates cancer cell invasion

This study shows that loss of DMT1 disrupts iron homeostasis, leading to ER stress and ECM destabilization, which enhances cancer cell invasion in 3D models.

Real-Time Wide-Field Fluorescence Lifetime Imaging via Single-Snapshot Acquisition for Biomedical Applications

This paper introduces a real-time fluorescence lifetime imaging method using single-snapshot acquisitions, demonstrating its application in biomedical scenarios from microscopic to macroscale.

Depth-Resolved Macroscopic Fluorescence Lifetime Imaging via High-Spatial-Frequency Structured Illumination

This paper introduces HSF-FLI, a method to isolate subsurface fluorescence signals in MFLI, validated in vivo and ex vivo with mouse tumor models.

INKILN is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10

This paper identifies INKILN, a human-specific lncRNA that promotes vascular smooth muscle inflammation by stabilizing MKL1 and interacting with USP10.

Phosphorylation of GMFγ by c-Abl coordinates lamellipodial and focal adhesion dynamics

This study shows that c-Abl phosphorylates GMFγ at tyrosine-104, directing N-WASP to either protrusions or focal adhesions, thereby regulating cell migration.