Ann P. Wheeler

The paper identifies ER-liquid condensates that sequester FAM134B/C and RhoA, affecting cell morphology and cancer invasion.

This paper identifies JMJD5-ISY1-PRMT6 as a pathway regulating metabolism by hydroxylating ISY1 to inhibit PRMT6, showing its role in liver cancer and potential as a therapeutic target.

The paper shows chronic lysosome damage from Palbociclib treatment in cancer cells triggers interferon responses via mitochondrial nucleic acid release, dependent on lysosome-mitochondrion contacts.

This study shows that DNMT3B PWWP mutations cause hypermethylation of heterochromatin marked by H3K9me3, disrupting DNA methylation homeostasis and contributing to ICF syndrome, cancer, and aging.

The paper shows how periodic GTPase waves coordinate leading and trailing edge dynamics during cell migration through RhoA-Rac1 interactions.