Author

Artem Lomakin

European Bioinformatics InstituteORCID 0000-0002-6568-9668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Moritz GerstungiD· 2 shared Oliver StegleiD· 2 shared Adam GayosoiD· 1 shared Alexander Aivazidis· 1 shared Anna ArutyunyaniD· 1 shared Artem ShmatkoiD· 1 shared Christina N. CurtisiD· 1 shared Darjus Felix TschaharganehiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Moritz GerstungORCID

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3 papers

Recent·Most cited

Enforced ZFP281 expression delays breast cancer initiation and can provide lifelong protection against breast cancer metastasis

Deepak Kumar Singh, Hongwei Zhou, Nyima Sherpa, Xiang Yu Zheng, Artem Lomakin, Pedram Razghandi, Xin Hunag, Rama Kadamb, Suryansh Shukla, Luis E. Valencia Salazar, David Entenberg, Deyou Zheng, Christina N. Curtis, Jianlong Wang, Julio A. Aguirre‐Ghiso

This study shows that ZFP281 expression delays breast cancer initiation and prevents metastasis by enforcing a dormant state in cancer cells.

bioRxiv · Apr 15, 2026 · PreprintCancer Biology

Integrated combinatorial functional genomics and spatial transcriptomics of tumors decodes genotype to phenotype relationships

Marco Breinig, Artem Lomakin, Elyas Heidari, Michael A. Ritter, Gleb D. Rukhovich, Lio Böse, Luise Butthof, Lena Wendler-Link, Hendrik Wiethoff, Tanja Poth, Felix Sahm, Peter Schirmacher, Oliver Stegle, Moritz Gerstung, Darjus Felix Tschaharganeh

The paper introduces CHOCOLAT-G2P, a method integrating functional genomics and spatial transcriptomics to study genotype-phenotype relationships in tumors, revealing zonation patterns and epistasis in liver cancer.

Nature Biomedical Engineering · Jul 28, 2025Peer-reviewedCancer Biology

Cell2location maps fine-grained cell types in spatial transcriptomics

Vitalii Kleshchevnikov, Artem Shmatko, Emma Dann, Alexander Aivazidis, Hamish W. King, Tong Li, Rasa Elmentaite, Artem Lomakin, Veronika R. Kedlian, Adam Gayoso, Mika Sarkin Jain, Jun Sung Park, Lauma Ramona, Elizabeth J. Tuck, Anna Arutyunyan, , Omer Ali Bayraktar

cell2location uses a Bayesian model to integrate single-cell and spatial transcriptomics, mapping cell types in situ across mouse brain regions and human lymph node immune compartments.

Nature Biotechnology · Jan 13, 2022Peer-reviewedBioinformatics