Author

Luis E. Valencia Salazar

Albert Einstein College of MedicineORCID 0000-0002-5499-1394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Julio A. Aguirre‐GhisoiD· 2 shared Artem LomakiniD· 1 shared Beatriz del Valle‐PéreziD· 1 shared Christina N. CurtisiD· 1 shared Dalong QianiD· 1 shared David Entenberg· 1 shared Debashis SahooiD· 1 shared Deepak Kumar SinghiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Julio A. Aguirre‐GhisoORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 10, 2026

A Developmental Lectin-Glycan Program Enables Early Breast Cancer Dissemination and Metastatic Onset

Ramiro M. Perrotta, Magalí Bertón, Luis E. Valencia Salazar…·Mariana Salatino

This study identifies a developmental GAL1-glycan program that promotes early breast cancer dissemination and metastasis by reactivating mammary stem cell traits and epithelial plasticity.

DOI 10.64898/2026.02.23.707584

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintApr 15, 2026

Enforced ZFP281 expression delays breast cancer initiation and can provide lifelong protection against breast cancer metastasis

Deepak Kumar Singh, Hongwei Zhou, Nyima Sherpa…·Julio A. Aguirre‐Ghiso

This study shows that ZFP281 expression delays breast cancer initiation and prevents metastasis by enforcing a dormant state in cancer cells.

DOI 10.64898/2026.04.13.718280

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJan 22, 2025

The E2F4 transcriptional repressor is a key mechanistic regulator of colon cancer resistance to irinotecan (CPT-11).

Junichi Matsubara, Yong Fuga Li, Sanjay Koul…·Piero D. Dalerba

This study identifies E2F4 as a key regulator of colon cancer resistance to irinotecan by showing its role in drug resistance through shRNA knockdown in PDX models.

2 citations

humanmouse

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