Patricia Yuste‐Checa

This study shows that tau aggregates can be packaged into lentiviral particles and induce tau aggregation in recipient cells, suggesting a potential mechanism linking viral infections to neurodegenerative diseases.

This study shows that proteostatic stress in mitochondria impairs mitoribosome biogenesis and translation, leading to respiratory deficiency and mitochondrial DNA loss.

This study shows that alpha-synuclein fibrils sequester and degrade ESCRT-III proteins, leading to endolysosomal damage and increased alpha-synuclein aggregation.

This study identifies hydrophobic peptide tails in clusterin as essential for its chaperone function and lipid binding, enabling diverse roles in protein clearance and lipoprotein formation.