Maximina Hee Yun

This study shows that adaptive immune cells are not required for appendage regeneration in axolotls and zebrafish, with regeneration proceeding normally despite the absence of mature T and B cells.

This study investigates MHC evolution in seven newt species, finding a compact core MHC region and lineage-specific duplications, challenging previous assumptions about MHC expansion in giant genomes.

The paper presents the chromosome-scale assembly of the giant Pleurodeles waltl genome, revealing insights into its expansion and regeneration-related genes.

This study identifies hypoxia as an inhibitor of newt skeletal muscle dedifferentiation through transcriptomic analysis of myotube differentiation and dedifferentiation.

The paper introduces the Amphibian Genomics Consortium to address gaps in amphibian genomic resources and promote international collaboration for research and conservation.

This study develops epigenetic clocks for axolotls, revealing biphasic age prediction during early life but not later, and highlights methylome stability across lifespan.

This study shows that macrophages are essential for lens regeneration in newts by reducing fibrosis, modulating inflammation, and balancing cell proliferation and apoptosis.

This study shows that manipulating SLAP expression during brain development affects cortical lamination and exploratory behavior in mice.

This study shows that cellular senescence promotes progenitor cell expansion during axolotl limb regeneration by creating a pro-proliferative niche and modulating Wnt signaling.

The paper identifies conserved notochord-specific enhancers of Brachyury/T/TBXT in vertebrates and shows their role in notochord expression and development.

This study shows that senescent cells promote muscle dedifferentiation and enhance newt limb regeneration through secreted factors and the FGF-ERK signaling pathway.

This study identifies cell type innovations in salamander forebrain evolution, showing similarities to both sauropsid DVR and mammalian neocortex.

The paper shows that the newt Pleurodeles waltl maintains telomeres without telomerase, using ALT for whole-organism telomere length preservation.

The paper identifies Tig1 as a regulator of proximo-distal identity during salamander limb regeneration through single-cell RNAseq analysis.

The paper identifies a conserved regulatory program driving lateral plate mesoderm emergence across chordates using zebrafish and comparative analysis.