Emma L. Moore

This study identifies NR6A1 as a critical regulator of mammalian neural crest cell specification, formation, and survival through loss-of-function experiments and multiomic analyses.

The paper identifies and characterizes intermediate states during neural crest cell epithelial to mesenchymal transition and delamination using single-cell RNA sequencing.

The paper identifies a novel mechanism of neural crest cell delamination through cell extrusion, revealing PIEZO1's role in this process in mouse embryos.

The paper shows that rRNA transcription by Pol I is essential for nucleolar structure and liquid-liquid phase separation in mouse embryos.

The paper shows that disruptions in Pol I rRNA transcription specifically affect craniofacial development by causing NCC apoptosis and craniofacial anomalies in mice.

This study identifies Nr6a1 as a master regulator of trunk-specific axial development in mice, controlling elongation, segmentation, and lineage allocation through Hox gene regulation and gene regulatory networks.

The paper identifies Osterix as a downstream effector of AMH signaling that regulates Mullerian duct regression through transcriptome analysis of fetal MD mesenchymal cells.