Shizue Omi

Quantitative biophysical analysis of human septin hexamer and octamer self-assembly on model membranes

This study quantitatively compares the membrane binding and self-assembly of human septin hexamers and octamers using biophysical methods, revealing distinct structural properties and functional implications.

Genetically encoded reporters of actin filament organization in living cells and tissues

This paper develops genetically encoded fluorescent reporters to quantify actin filament organization in living cells and tissues using fluorescence polarization microscopy.

A defining member of the new cysteine-cradle family is an aECM protein signalling skin damage in C. elegans

The paper identifies spia-1 as a gene involved in immune activation in C. elegans by sensing cuticle damage through its secreted protein with a novel cysteine-cradle domain.

New strains for tissue-specific RNAi studies in Caenorhabditis elegans

The paper evaluates tissue-specific RNAi strains in C. elegans and identifies a suitable genetic background for constructing robust tissue-specific RNAi strains.

Modulatory upregulation of an insulin peptide gene by different pathogens in C. elegans

This study shows that ins-11, an insulin peptide gene in C. elegans, is upregulated by different pathogens in specific tissues and influences immune responses and longevity.