BioengineeringbioRxivPreprint
Low-density lipoprotein receptor-targeting chimeras for membrane protein degradation and enhanced drug delivery
Fangzhu Zhao, Yan Wu, Kaitlin Schaefer…·James A. Wells
This paper develops LIPTACs, LDLR-targeting chimeras that enhance lysosomal delivery and cytotoxicity for cancer treatment by combining eTPD and ADC strategies.
4 citations