Daniel G. Bunis

A Transcriptomics-Based Computational Drug Repurposing Pipeline Identifies Simvastatin And Primaquine As Therapeutics For Endometriosis

This study identifies simvastatin and primaquine as potential therapeutics for endometriosis through computational drug repositioning, showing reduced pain and gene expression changes in animal models and lower disease risk in EMR data.

Differential Assembly of Mouse and Human Tumor Microenvironments

The paper compares mouse and human tumor microenvironments, identifying conserved and species-specific features in immune composition and gene expression programs.

Searching for influencers among placental immune cells in preeclampsia.

The paper identifies SPP1 and CD44 as influencers of inflammation in preeclampsia by analyzing single-cell transcriptional profiles of placental immune cells.

Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosis

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

A computational drug repositioning pipeline identifies potential therapeutics for COVID-19 by matching SARS-CoV-2 gene expression signatures to drug profiles.