Author

Iva Nikolić

Peter MacCallum Cancer CentreORCID 0000-0002-0141-5975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Das· 1 shared Andrew J. DeansiD· 1 shared Antonia L. CadelliD· 1 shared Carla L. AlvesiD· 1 shared Catherine Elizabeth CaldoniD· 1 shared Celine E Wiharja· 1 shared Ching‐Seng AngiD· 1 shared Christine S Lee· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Andrew Das

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2 papers

Recent·Most cited

Cell cycle dependent regulation of mRNA export in response to replication stress

Tobias D. Williams, Kirstyn T. Carey, William Hamilton, Linh H. Ngo, Sylvie van Twest, Vincent Murphy, Jieqiong Lou, Andrew Das, Emily Deeb, Ching‐Seng Ang, Iva Nikolić, Karla J. Cowley, Kaylene Simpson, Kristin Brown, Elizabeth Hinde, , Vihandha O. Wickramasinghe

The paper identifies WEE1, CDK1, and PLK1 as regulators of mRNA export during DNA replication stress, showing their role in preventing R-loop associated mRNA from being exported to the cytoplasm.

bioRxiv · Sep 9, 2026 · PreprintMolecular Biology

JNK pathway suppression drives resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer

Sarah Alexandrou, Christine S Lee, Kristine J. Fernandez, Celine E Wiharja, Leila Eshraghi, John Reeves, Daniel A. Reed, Neil Portman, Zoe Phan, Heloisa Helena Milioli, Iva Nikolić, Antonia L. Cadell, David R. Croucher, Kaylene J. Simpson, Elgene Lim, , Catherine Elizabeth Caldon

This study identifies JNK pathway suppression as a driver of resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer, with implications for patient stratification.

bioRxiv · Jan 8, 2025 · PreprintCancer Biology