Omer Revah

Information processing-like phenotype of human brain organoids

This study quantifies information-processing-like properties of human cortical organoids using a functional phenotyping framework, linking network function to disease-related mutations and pharmacological perturbations.

Coding in cortical subpopulations critically depends on fine-tuning of cell physiology

The paper shows that population coding in cortical neurons depends on precise physiological parameters, validated through experiments on mouse barrel cortex neurons.

The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion

This study identifies cholecystokinin (CCK) as the primary regulator of gonadotropin secretion in zebrafish, showing it controls ovarian development and FSH release.

Assembloid model to study loop circuits of the human nervous system

The paper develops an assembloid model of the human cortico-striatal-thalamic-cortical circuit to study its function and disease-related disruptions.

Dynamic gain decomposition reveals functional effects of dendrites, ion channels and input statistics in population coding

The paper decomposes the dynamic gain function to attribute network-level encoding features to specific cell-level parameters in neurons and models.

Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway

This study uses human assembloids to investigate how CACNA1G gene variants affect thalamocortical pathway function in neuropsychiatric disorders.

Dissecting the molecular basis of human interneuron migrationin forebrain assembloids from Timothy syndrome

This study investigates interneuron migration defects in Timothy syndrome using human forebrain assembloids and identifies pharmacological targets to rescue migration abnormalities.