Author

Yann Emmenegger

University of Lausanne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:electronic health records· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Paul FrankeniD· 5 shared Jeffrey T. HubbardiD· 4 shared Charlotte N. HoriD· 2 shared Marieke MB HoekstraiD· 2 shared Valérie MongrainiD· 2 shared Alejandro Osorio-ForeroiD· 1 shared Alexandre ReymondiD· 1 shared Ana Perez Caballero· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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5 shared papersNeuroscience

Paul FrankenORCID

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Author profile →

6 papers

Recent·Most cited

Lipid transport is necessary for neocortical lamination

Jacqueline Chrast, Stephan C. Collins, Catherine Roger, Siwar Ben-Ayache, Chiara Auwerx, Pauline Rogg, Fabrizio Vacca, Océane Musset, Lucie Gueneau, Yann Emmenegger, Fabienne Allias, Frédéric Tran Mau‐Them, Daniel C. Koboldt, Matthew Pastore, Kristen V. Truxal, , Alexandre Reymond

The paper investigates BLTP1's role in neocortical lamination by analyzing patients and mouse models, finding lipid transport defects cause structural brain abnormalities.

Genes & Diseases · May 1, 2026Peer-reviewedGenetics

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation

Najma Cherrad, Georgios Foustoukos, Laura M. J. Fernandez, Alejandro Osorio-Forero, Yann Emmenegger, Paul Franken, Anita Lüthi

The paper shows that vagal afferent activation induces brain-body cooling and NREM-sleep-like states while increasing locus coeruleus activity.

bioRxiv · Mar 14, 2025 · PreprintNeuroscience

Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner

Konstantinos Kompotis, Géraldine M. Mang, Jeffrey T. Hubbard, Sonia Jimenez, Yann Emmenegger, Christos Polysopoulos, Charlotte N. Hor, Leonore Wigger, Sébastien S. Hébert, Valérie Mongrain, Paul Franken

This study shows that miR-709 regulates NREM sleep EEG slow waves by linking glutamatergic signaling to neuronal activity through endosomal trafficking.

Proceedings of the National Academy of Sciences · Jan 11, 2024Peer-reviewedNeuroscience

Reassessing the validity of slow-wave dynamics as a proxy for NREM sleep homeostasis

Jeffrey T. Hubbard, Thomas C. Gent, Marieke MB Hoekstra, Yann Emmenegger, Valérie Mongrain, Hans‐Peter Landolt, Antoine Adamantidis, Paul Franken

The paper re-evaluates slow-wave dynamics as a proxy for NREM sleep homeostasis, finding distinct delta-wave types with different responses to sleep deprivation and recovery.

Nature Communications · Jun 19, 2020Peer-reviewedNeuroscience

Simple and complex interactions between sleep-wake driven and circadian processes shape daily genome regulatory dynamics in the mouse

Charlotte N. Hor, Jake Yeung, Maxime Jan, Yann Emmenegger, Jeffrey T. Hubbard, Ioannis Xénarios, Félix Naef, Paul Franken

This study examines how sleep deprivation affects gene expression and chromatin accessibility in mice, revealing long-term genomic regulatory changes.

Proceedings of the National Academy of Sciences · Nov 27, 2019Peer-reviewedGenomics

Cold Inducible RNA-binding protein (CIRBP) adjusts clock gene expression and REM sleep recovery after sleep deprivation

Marieke MB Hoekstra, Yann Emmenegger, Jeffrey T. Hubbard, Paul Franken

This study shows that CIRBP modulates clock gene expression and REM sleep recovery after sleep deprivation in mice.

eLife · Feb 5, 2019Peer-reviewedNeuroscience