Author

Siri Atma W. Greeley

University of ChicagoORCID 0000-0002-0741-3567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Aaron M. ZorniD· 1 shared Alan AshworthiD· 1 shared Alexander MarsoniD· 1 shared Amy L. PutnamiD· 1 shared Andrea L. Ferris· 1 shared Andrew P. MayiD· 1 shared Antoni RibasiD· 1 shared Baz Smith· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Aaron M. ZornORCID

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2 papers

Recent·Most cited

Human organoid modeling of congenital malformations caused by RFX6 mutations reveal an essential role for this transcription factor in establishing and maintaining duodenal identity upstream of PDX1

Jefferson G. Sanchez, Scott Rankin, Emily Paul, Heather A. McCauley, Daniel O. Kechele, Jacob R. Enriquez, Nana‐Hawa Yayah Jones, Siri Atma W. Greeley, Lisa Letourneau-Friedberg, Aaron M. Zorn, Mansa Krishnamurthy, James M. Wells

This study uses human organoids to show RFX6 mutations cause duodenal malformations by disrupting PDX1 and other signaling pathways.

bioRxiv · Nov 9, 2023 · PreprintDevelopmental Biology

Reprogramming human T cell function and specificity with non-viral genome targeting

Theodore L. Roth, Cristina Puig-Saus, Ruby Yu, Eric Shifrut, Julia C. Carnevale, P. Jonathan Li, Joseph B Hiatt, Justin D. Saco, Paige E. Krystofinski, Han Li, Victoria R. Tobin, David N. Nguyen, Michael R. Lee, Amy L. Putnam, Andrea L. Ferris, , Alexander Marson

This paper develops a non-viral CRISPR-Cas9 system for precise genome editing in human T cells, enabling therapeutic reprogramming of cell function and specificity.

Nature · Jul 1, 2018Peer-reviewedGenetics