Wesley H. Godfrey

This study identifies phosphoglycerate mutase (PGAM) as a regulator of Treg differentiation through serine synthesis and one-carbon metabolism, showing its impact on immune suppression and autoimmunity.

This study shows TPPB, a new PKC modulator, reduces neuroinflammation and promotes CNS repair in experimental MS by targeting innate immune cells.

The paper shows that bryostatin-1, a PKC modulator, shifts microglia and CNS macrophages from pro-inflammatory to regenerative states, promoting remyelination and neuroprotection in MS.

This study shows that blocking GAPDH nitrosylation with CGP3466b reduces neuroaxonal injury and disability in EAE, a model of multiple sclerosis, without affecting the immune system.