Author

Efrat Abramson

Johns Hopkins UniversityORCID 0000-0002-8677-4028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Michael D. KornbergiD· 3 shared Payam Mohammad GharibaniiD· 2 shared Shruthi ShanmukhaiD· 2 shared Soonmyung A. HwangiD· 2 shared Wesley H. GodfreyiD· 2 shared Adarsha P. MallaiD· 1 shared Chirag VasavdaiD· 1 shared Evan R. SemenzaiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Michael D. KornbergORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

Payam Mohammad Gharibani, Efrat Abramson, Shruthi Shanmukha, Matthew D. Smith, Wesley H. Godfrey, Judy J. Lee, Jingwen Hu, Maryna Baydyuk, Marie‐France Dorion, Xiaojing Deng, Yu Guo, Soonmyung A. Hwang, Jeffrey K. Huang, Peter A. Calabresi, Michael D. Kornberg, Paul M. Kim

The paper shows that bryostatin-1, a PKC modulator, shifts microglia and CNS macrophages from pro-inflammatory to regenerative states, promoting remyelination and neuroprotection in MS.

bioRxiv · Aug 28, 2023 · PreprintNeuroscience

Therapeutic Potential of Blocking GAPDH Nitrosylation with CGP3466b in Experimental Autoimmune Encephalomyelitis

Wesley H. Godfrey, Soonmyung A. Hwang, Kaho Cho, Shruthi Shanmukha, Payam Mohammad Gharibani, Efrat Abramson, Michael D. Kornberg

This study shows that blocking GAPDH nitrosylation with CGP3466b reduces neuroaxonal injury and disability in EAE, a model of multiple sclerosis, without affecting the immune system.

Frontiers in Neurology · Jan 24, 2023Peer-reviewedNeuroscience

D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain

Evan R. Semenza, Maged M. Harraz, Efrat Abramson, Adarsha P. Malla, Chirag Vasavda, Moataz M. Gadalla, Michael D. Kornberg, Solomon H. Snyder, Robin Roychaudhuri

This study identifies D-cysteine as an endogenous regulator of neural progenitor cell dynamics in the mammalian brain, showing its antiproliferative effects and role in cortical development.

Proceedings of the National Academy of Sciences · Sep 23, 2021Peer-reviewedNeuroscience