Author

Paul M Kim

Johns Hopkins UniversityORCID 0000-0002-9150-9536Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Michael D. KornbergiD· 2 shared Shruthi ShanmukhaiD· 2 shared Wesley H. GodfreyiD· 2 shared Xiaojing Deng· 2 shared Abu Hena Mostafa KamaliD· 1 shared Chandrashekar R. AmbatiiD· 1 shared Efrat AbramsoniD· 1 shared Jeffrey K. HuangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Michael D. KornbergORCID

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2 papers

Recent·Most cited

Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism

Wesley H. Godfrey, Judy J. Lee, Shruthi Shanmukha, Kaho Cho, Xiaojing Deng, Chandrashekar R. Ambati, Vasanta Putluri, Abu Hena Mostafa Kamal, Paul M Kim, Nagireddy Putluri, Michael D. Kornberg

This study identifies phosphoglycerate mutase (PGAM) as a regulator of Treg differentiation through serine synthesis and one-carbon metabolism, showing its impact on immune suppression and autoimmunity.

eLife · Jan 30, 2025Peer-reviewedImmunology

PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

Payam Mohammad Gharibani, Efrat Abramson, Shruthi Shanmukha, Matthew D. Smith, Wesley H. Godfrey, Judy J. Lee, Jingwen Hu, Maryna Baydyuk, Marie‐France Dorion, Xiaojing Deng, Yu Guo, Soonmyung A. Hwang, Jeffrey K. Huang, Peter A. Calabresi, Michael D. Kornberg, Paul M. Kim

The paper shows that bryostatin-1, a PKC modulator, shifts microglia and CNS macrophages from pro-inflammatory to regenerative states, promoting remyelination and neuroprotection in MS.

bioRxiv · Aug 28, 2023 · PreprintNeuroscience