Author

John M. Dye

United States Army Medical Research Institute of Infectious DiseasesORCID 0000-0002-0883-5016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Abhinay GontuiD· 1 shared Aditi AgrawaliD· 1 shared Amrita OjhaiD· 1 shared Andre C. MaranhaoiD· 1 shared Andrew D. EllingtoniD· 1 shared Andrew J. BorstiD· 1 shared Andrew P. HortoniD· 1 shared Andrew S. HerbertiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperSynthetic Biology

Abhinay GontuORCID

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Author profile →

3 papers

Recent·Most cited

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Marwah Karim, Manjari Mishra, Chieh‐Wen Lo, Sirle Saul, Halise Busra Cagirici, Manon Gourdelier, Luca Ghita, Amrita Ojha, Tran Do Hoang Nhu, Aditi Agrawal, Connor McGraw, Michael P. East, Karen Anbro Gammeltoft, Malaya Kumar Sahoo, Nancie A. Mooney, , Shirit Einav

RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.

Nature Communications · Jul 10, 2025Peer-reviewedMicrobiology

A Multivalent Pan-Ebolavirus Nanoparticle Vaccine Provides Protection in Rodents from Lethal Infection by Adapted Zaire and Sudan Viruses

Natalie Brunette, Connor Weidle, Samuel P. Wrenn, Brooke Fiala, Rashmi Ravichandran, Kenneth D. Carr, Samantha E. Zak, Elizabeth E. Zumbrun, Russell R. Bakken, Michael Murphy, Sidney Chan, Rebecca Skotheim, Andrew J. Borst, Lauren P. Carter, Colin Correnti, , Lance J. Stewart

This study develops a multivalent nanoparticle vaccine against EBOV and SUDV, showing protection in rodents from lethal infection.

bioRxiv · Jan 29, 2025 · PreprintImmunology

Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality

Jule Goike, Ching‐Lin Hsieh, Andrew P. Horton, Elizabeth C. Gardner, Foteini Bartzoka, Nianshuang Wang, Kamyab Javanmardi, Andrew S. Herbert, Shawn A. Abbasi, Rebecca L. Renberg, Michael J. Johanson, José Cardona, Thomas H. Segall-Shapiro, Ling Zhou, Ruth Helmus Nissly, , Jimmy Gollihar

The paper identifies SARS-CoV-2 neutralizing antibodies from convalescent patients and describes a novel quaternary binding mechanism using high-throughput methods.

bioRxiv · Apr 7, 2021 · PreprintSynthetic Biology