Author

William E. Martenis

Broad InstituteORCID 0000-0002-1520-5717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Evan P. LeboisiD· 2 shared Katherine J. StalnakeriD· 2 shared Michel WeïweriD· 2 shared Morgan ShengiD· 2 shared Adam Skepner· 1 shared Alex Guletsky· 1 shared Alexander J. FittiD· 1 shared Alexandra E. GouldiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

Evan P. LeboisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacology & ToxicologyACS Chemical NeurosciencePeer-reviewedOct 29, 2026

Discovery of GluA3 preferring AMPA receptor positive allosteric modulator BRD3290

Christopher Greaves, William E. Martenis, Shawn Dwayne Nelson…·Sean P. Moran

This study discovers BRD3290, a GluA3-preferring AMPA receptor PAM, but finds it does not improve cognitive function in mice despite target engagement.

DOI 10.1021/acschemneuro.6c00573

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 26, 2025

The G-protein coupled receptor GPR34 maintains the homeostatic state of microglia and restrains the disease-associated microglial response in an Alzheimers disease model

Ana Geller, Min Jee Kwon, Sean Simmons…·Prabhat S. Kunwar

This study shows that GPR34 maintains microglial homeostasis and limits disease-associated microglial responses in Alzheimer's disease models.

1 citation

mousehuman

𝕏 PostBluesky

Developmental BiologyInsect Biochemistry and Molecular BiologyPeer-reviewedNov 3, 2020

The oncometabolite L-2-hydroxyglutarate is a common product of Dipteran larval development

Nader H. Mahmoudzadeh, Alexander J. Fitt, Daniel B. Schwab…·Jason M. Tennessen

The paper investigates L-2-hydroxyglutarate (L-2HG) accumulation in 18 insect species, finding high levels in Dipterans and suggesting a potential role in their development and pest control.

12 citations

DrosophilaArabidopsis

𝕏 PostBluesky