Ian J. Deary

This study investigates shared genetic architecture between subcortical brain volumes and MDD using GWAS data from multiple cohorts, finding a non-significant positive genetic correlation for hippocampal volume.

This study conducts a GWAS of alcohol consumption in UK Biobank, identifying 8 loci, including novel associations, and reports genetic overlaps with schizophrenia, HDL cholesterol, smoking, and anthropometric traits.

This study finds reduced white matter integrity in individuals with major depressive disorder using UK Biobank imaging data, but no significant subcortical volume differences.

This study identifies genetic variants associated with epigenetic age acceleration and shows TERT's role in regulating the DNA methylation clock.

The paper investigates rare disruptive variants in the DISC1 Interactome and Regulome, finding associations with schizophrenia and cognitive ability in psychiatric patients.

The paper examines the genetic architectures of two neuroticism factors and finds they are associated with positive outcomes like affluence and longer life, unlike the general neuroticism factor.

This study uses Mendelian randomization to examine causal relationships between cognitive ability, educational attainment, and physical health traits, finding no evidence of causation from health to cognitive ability or from educational attainment to health.

This study investigates the association between CpG methylation and educational attainment, finding limited significant associations that may be influenced by confounding factors.

The paper evaluates 15 candidate SNPs associated with psychiatric disorders using 6,165 diffusion MRI scans, finding no significant associations after correction for multiple testing.

This study examines the genetic overlap between major psychiatric disorders and brain structure in UK Biobank data but finds no significant associations.

This study identifies that genetic variants associated with cognitive function are enriched in evolutionarily conserved regions, which account for a significant portion of heritability.

This study investigates the interaction between polygenic risk scores for schizophrenia and major depressive disorder (MDD) in two cohorts, finding reduced case-control differences in distress and neuroticism with higher schizophrenia risk.

This study identifies over 250 genetic loci associated with severe hair loss using UK Biobank data and develops a prediction algorithm with an AUC of 0.82.

This study identifies genetic and environmental factors contributing to chronic pain and its link to major depressive disorder using data from Generation Scotland and UK Biobank.