Author

Tobias Schmid

Goethe University FrankfurtORCID 0000-0002-1952-5259Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Anica Scholz· 2 shared Bernhard BrüneiD· 2 shared Kathi ZarnackiD· 2 shared Rolf BackofeniD· 2 shared Ajay M. Shah· 1 shared Andrea Hildebrandt· 1 shared Andrea Voigt· 1 shared Anke BuschiD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Anica Scholz

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Author profile →

4 papers

Recent·Most cited

Enhanced IGFL1 translation in response to IL-1β is controlled by distinct 3UTR elements

Giulia Cardamone, Melanie Flohr, Rebecca Raue, Irina I. Bode, Sofie Patrizia Meyer, Sven Hauns, Rolf Backofen, Tobias Schmid

The paper shows IL-1β enhances IGFL1 translation through a G-rich 3UTR element in MCF7 cells.

PLoS ONE · Jun 25, 2026Peer-reviewedMolecular Biology

The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A)-translation

Andrea Hildebrandt, Mirko Brüggemann, Cornelia Rücklé, Susan Boerner, Jan B. Heidelberger, Anke Busch, Heike Hänel, Andrea Voigt, Martin M. Möckel, Stefanie Ebersberger, Anica Scholz, Annabelle Dold, Tobias Schmid, Ingo Ebersberger, Jean‐Yves Roignant, , Petra Beli

This study identifies MKRN1 as a key player in ribosome-associated quality control by promoting ribosome stalling at poly(A) sequences to prevent erroneous protein production.

Genome biology · Oct 22, 2019Peer-reviewedMolecular Biology

uORF-Tools - Workflow for the determination of translation-regulatory upstream open reading frames

Anica Scholz, Florian Eggenhofer, Rick Gelhausen, Björn Andreas Grüning, Kathi Zarnack, Bernhard Brüne, Rolf Backofen, Tobias Schmid

The paper introduces a workflow for identifying functional upstream open reading frames (uORFs) using ribosome profiling data and provides a human uORF annotation file.

PLoS ONE · Sep 12, 2019Peer-reviewedBioinformatics

Hydrogen peroxide formation by Nox4 limits malignant transformation

Valeska Helfinger, Florian Freiherr von Gall, Nina Henke, Michael M. Kunze, Tobias Schmid, Juliana Heidler, Ilka Wittig, Heinfried H. Radeke, Viola Marschall, Karen Anderson, Ajay M. Shah, Simone Fulda, Bernhard Brüne, Ralf P. Brandes, Katrin Schröder

The paper shows that Nox4 produces hydrogen peroxide, which prevents malignant transformation by regulating DNA repair and AKT activity.

bioRxiv · Aug 16, 2017 · PreprintCancer Biology