Author

Raphael David Levine

University of California, Los AngelesORCID 0000-0002-1973-8449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

James R. HeathiD· 2 shared Alphonsus H. C. NgiD· 1 shared Antoni RibasiD· 1 shared Charles WardeniD· 1 shared Chunmei Liu· 1 shared Daniel CheniD· 1 shared David BaltimoreiD· 1 shared Dazy Johnson· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

James R. HeathORCID

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2 papers

Recent·Most cited

Decoding Spatial Programs in Human Glioblastoma Through Surprisal Information-Theoretical Analysis

Shuozhen Bao, Gretchen Long, Shouryo Ghose, N.-K. Wang, Haikuo Li, Mei Zhong, Logan Carter Matthews, Yao Lu, Jie Sheng, Zewei Tu, William Escobar, Pallavi P. Gopal, Declan McGuone, Zeynep Erson-Omay, Khaled Alok, , Rong Fan

This paper uses surprisal information-theoretic analysis on spatial transcriptomic data from human glioblastoma to uncover hidden spatial programs and interactions not detected by standard methods.

bioRxiv · Jun 24, 2026 · PreprintSystems Biology

Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer

Yapeng Su, Chunmei Liu, Xiang Lu, Hui-Yu Chuang, Guideng Li, Shiqun Shao, Yan Kong, Jihoon William Lee, Rachel H. Ng, Stephanie Wong, Lídia Robert, Charles Warden, Victoria Liu, Jie Chen, Zhuo Wang, , Wei Wei

This study identifies NF-κB-driven chromatin remodeling as a mechanism for drug-induced dedifferentiation in cancer, revealing its role in promoting drug-tolerant persister states.

Nature Communications · Apr 15, 2026Peer-reviewedCancer Biology