Author

Margaret C.W. Ho

Johns Hopkins UniversityORCID 0000-0002-2007-2226Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:electronic health records· 1 Assay:imaging· 1

Frequent Co-Authors

Mark N. WuiD· 2 shared Abdulsalam AdegokeiD· 1 shared Adam X. MirandaiD· 1 shared Colton McNinchiD· 1 shared El‐Sayed BaziD· 1 shared Emily Han· 1 shared Forrest H. HoytiD· 1 shared Habon A. IssaiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Mark N. WuORCID

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3 papers

Recent·Most cited

Insights into tick-pathogen interactions - a single cell RNA sequencing approach of transcriptional changes during ehrlichial infection

Abdulsalam Adegoke, Joseph A. Aspinwall, Colton McNinch, Margaret C.W. Ho, Adam X. Miranda, Forrest H. Hoyt, Vinod Nair, Justin Lack, Taís B. Saito

This study uses single-cell RNA sequencing to analyze transcriptional changes in ISE6 tick cells during Ehrlichia muris eauclairensis infection, revealing distinct cell states and time-dependent gene expression patterns.

bioRxiv · Mar 20, 2026 · PreprintMolecular Biology

Astroglial Calcium Signaling Encodes Sleep Need in Drosophila

Ian David Blum, Mehmet F. Keleş, El‐Sayed Baz, Emily Han, Kristen H. Park, Skylar Luu, Habon A. Issa, Matthew P. Brown, Margaret C.W. Ho, Masashi Tabuchi, Sha Liu, Mark N. Wu

The paper shows that astroglial calcium signaling in Drosophila increases with sleep need and is required for homeostatic sleep rebound, identifying TyrRII as a key receptor involved in this process.

Current Biology · Nov 12, 2020Peer-reviewedNeuroscience

Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay

Xitong Liang, Margaret C.W. Ho, Yajun Zhang, Yulong Li, Mark N. Wu, Timothy E. Holy, Paul H. Taghert

The paper identifies a circadian pathway in Drosophila where morning and evening oscillators drive pre-motor centers via specific dopaminergic neurons, resulting in a two-peak locomotor activity pattern.

Neuron · Apr 10, 2019Peer-reviewedNeuroscience