Antoine Gedeon

This paper validates Corynebacterium glutamicum as a non-pathogenic surrogate for Mycobacterium tuberculosis to study DNA gyrase and discover new inhibitors.

This study defines the structural basis of MfpD function using phylogenetic, structural, and biophysical approaches, revealing its role in promoting GTP hydrolysis by MfpB through a noncanonical mechanism.

This study investigates the structural and functional organization of the de novo purine nucleotide biosynthetic pathway enzymes in Pseudomonas aeruginosa, revealing a metabolon-like complex with potential antibiotic implications.

The paper investigates echinocandin resistance in Candida species, finding that increased consumption did not lead to significant resistance, but mutations in glucan synthase genes affect fitness differently across species.