Marlene M. Hao

Timed binary WNT activity is sufficient to model the early human neural axis

This paper shows that timed WNT pulses can specify distinct neural domains in human pluripotent stem cells, enabling the generation of specific neuron and progenitor types.

A neuroimmune IL-13 axis is associated with human enteric nervous system development

This study identifies a neuroimmune IL-13 axis involved in human enteric nervous system development through transcriptomic and functional analyses of neonatal ileum tissue.

Multi-omic and spatial analysis reveals tumour-derived paracrine signals drive suppressive macrophage polarisation via activation of the cAMP-CREB axis in glioblastoma

A call for a unified and multimodal definition of cellular identity in the enteric nervous system

The paper highlights the need for a unified multimodal approach to define cellular identity in the enteric nervous system using transcriptomic and other omics data.

Luminal nutrients activate distinct patterns in submucosal and myenteric neurons in the mouse small intestine

The paper shows that different luminal nutrients activate distinct calcium responses in submucosal and myenteric neurons of the mouse small intestine.