Author

Frances S. Cho

Gladstone InstitutesORCID 0000-0002-2576-7801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Assay:electronic health records· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jeanne T. PaziD· 4 shared Bryan T. HigashikuboiD· 2 shared Agnieszka CiesielskaiD· 1 shared Akshaj Joshi· 1 shared Alejandro Osorio-ForeroiD· 1 shared Alexandra Clemente-Perez· 1 shared Allison R. MorningstariD· 1 shared Andrea J. TenneriD· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Jeanne T. PazORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

A Dual Inhibitory Network in the Thalamic Reticular Nucleus Delineated by Pallidal and Intra-Reticular Inhibition

Frances S. Cho, John R. Huguenard, Jeanne T. Paz

The paper identifies a dual inhibitory network in the thalamic reticular nucleus (TRN) involving intra-TRN and pallidal inputs, revealing subtype-specific connectivity and complementary mechanisms for thalamic signal gating.

bioRxiv · Oct 5, 2025 · PreprintNeuroscience

Entorhinal cortex represents task-relevant remote locations independent of CA1

Emily A Aery Jones, Isabel I. C. Low, Frances S. Cho, Lisa Marie Giocomo

The paper shows that MEC neurons represent remote task-relevant locations during immobility, independent of CA1 activity.

bioRxiv · Jul 23, 2024 · PreprintNeuroscience

Complement factor C1q mediates chronic neuron loss and inflammation post-brain injury

Stephanie S. Holden, Fiorella Carla Grandi, Oumaima Aboubakr, Bryan T. Higashikubo, Frances S. Cho, Andrew H. Chang, Alejandro Osorio-Forero, Allison R. Morningstar, Vidhu Mathur, Logan J. Kuhn, Poojan Suri, Sethu Sankaranarayanan, Yaisa S. Andrews-Zwilling, Andrea J. Tenner, Anita Lüthi, , Jeanne T. Paz

This study shows that C1q mediates chronic neuron loss and inflammation after brain injury by targeting the corticothalamic circuit in mice.

Science · Sep 9, 2021Peer-reviewedNeuroscience

Interleukin-33 coordinates a microglial phagocytic response and limits corticothalamic excitability and seizure susceptibility

Rafael Taeho Han, Ilia D. Vainchtein, Johannes C. M. Schlachetzki, Frances S. Cho, Leah C. Dorman, Tessa Johung, Eunji Ahn, Jerika J. Barron, Hiromi Nakao-Inoue, Akshaj Joshi, Ari B. Molofsky, Christopher K. Glass, Jeanne T. Paz, Anna Victoria Molofsky

This study identifies IL-33's role in microglial phagocytosis and its impact on synaptic refinement and seizure susceptibility in the developing brain.

bioRxiv · Aug 5, 2021 · PreprintNeuroscience

Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin-positive neurons in reticular thalamus

Mahmood S. Hoseini, Bryan T. Higashikubo, Frances S. Cho, Andrew H Chang, Alexandra Clemente-Perez, Irene Lew, Agnieszka Ciesielska, Michael P. Stryker, Jeanne T. Paz

The paper shows that somatostatin-positive neurons in the reticular thalamus modulate visual information and gamma activity in V1 and dLGN in behaving mice.

eLife · Apr 12, 2021Peer-reviewedNeuroscience