Author

Morgan R. Timm

Washington University in St. LouisORCID 0000-0002-2947-9508Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron J. SchmitziD· 2 shared Ali H. EllebedyiD· 2 shared Denise A. SanickiD· 2 shared Edward D. B. LopattoiD· 2 shared Jerome S. PinkneriD· 2 shared Karen DodsoniD· 2 shared Scott J. HultgreniD· 2 shared Adam M. Chazin-GrayiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Aaron J. SchmitzORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

De Novo Design of Miniprotein Inhibitors of Bacterial Adhesins

Adam M. Chazin-Gray, Tuscan Rock Thompson, Edward D. B. Lopatto, Pearl Magala, Patrick W. Erickson, Andrew C. Hunt, Anna A. Manchenko, Pavel Aprikian, Veronika L Tchesnokova, Irina Basova, Denise A. Sanick, Kevin O. Tamadonfar, Morgan R. Timm, Jerome S. Pinkner, Karen Dodson, , David A. Baker

This study designs miniprotein inhibitors targeting bacterial adhesins to prevent and treat urinary tract infections.

Nature Communications · Oct 9, 2026Peer-reviewedMicrobiology

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

Edward D. B. Lopatto, Jesús M. Santiago-Borges, Denise A. Sanick, Sameer Kumar Malladi, Philippe N. Azimzadeh, Morgan R. Timm, Isabella F. Fox, Aaron J. Schmitz, Jackson S. Turner, Shaza M. Sayed Ahmed, Lillian Ortinau, Nathaniel C. Gualberto, Jerome S. Pinkner, Karen Dodson, Ali H. Ellebedy, , Scott J. Hultgren

This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.

Science Advances · Jun 20, 2025Peer-reviewedMicrobiology