Author

Ela W. Knapik

Vanderbilt UniversityORCID 0000-0002-2977-3619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Organism:zebrafish· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Dharmendra Choudhary· 2 shared Dylan RitteriD· 2 shared Abigail C. NeiningeriD· 1 shared Alaina H. WilletiD· 1 shared Alexandra ScaliciiD· 1 shared Brittany J. Bisnett· 1 shared Cynthia A. Reinhart‐KingiD· 1 shared Daniel S. LeviciD· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Dharmendra Choudhary

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Author profile →

5 papers

Recent·Most cited

Common variant approaches to study Mendelian disease gene function identify novel phenome and pathways associated with PLOD3

Alexandra Scalici, James T. Baker, Freida Blostein, Megan M. Shuey, Dharmendra Choudhary, Ela W. Knapik, David C. Samuels, Jennifer Elizabeth Below, Lisa A. Bastarache, Tyne W. Miller‐Fleming, Nancy Jean Cox

medRxiv · Nov 25, 2025 · PreprintGenetic & Genomic Medicine

A non-muscle α-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling

James B. Hayes, Dharmendra Choudhary, Dylan Ritter, Abigail C. Neininger, Alaina H. Willet, Leah R. Caplan, Yu Wang, Xiao Liu, Nilay Taneja, Zachary Sanchez, Kyra Smart, David Armstrong, Cynthia A. Reinhart‐King, Qi Liu, Matthew J. Tyska, , Dylan Tyler Burnette

This study identifies ACTN4 as a non-muscle α-actinin in cardiac sarcomeres, showing it regulates contractility, hypertrophy, and heart remodeling without disease hallmarks.

Circulation Research · Nov 19, 2025Peer-reviewedCell Biology

Dynamic regulation of the COPII interactome and collagen trafficking by site-specific glycosylation of Sec24D

Tetsuya Hirata, Dharmendra Choudhary, Brittany J. Bisnett, Erik J. Soderblom, Ela W. Knapik, Michael Boyce

The paper shows that O-GlcNAcylation of Sec24D regulates collagen trafficking by modulating its interactome and interaction with myoferlin in human cells and zebrafish.

bioRxiv · Jun 13, 2025 · PreprintCell Biology

A pre-vertebrate endodermal origin of calcitonin-producing neuroendocrine cells

Jenaid M. Rees, Katie Kirk, Giacomo Gattoni, Dorit Hockman, Victoria A. Sleight, Dylan Ritter, Èlia Benito‐Gutiérrez, Ela W. Knapik, Justin Gage Crump, Péter Fábián, J. Andrew Gillis

The paper traces the embryonic origin of calcitonin-producing cells across vertebrates and finds they derive from pharyngeal endoderm, not neural crest, and identifies homologues in invertebrate chordates.

Development · Aug 7, 2024Peer-reviewedDevelopmental Biology

Regulated extracellular matrix trafficking shapes cell growth during cartilage morphogenesis

Daniel S. Levic, Gökhan Ünlü, David B. Melville, Ela W. Knapik

This study identifies Erc1b as a genetic factor for craniofacial syndromes by showing its role in regulating ECM trafficking and chondrocyte growth in zebrafish.

bioRxiv · Jun 8, 2022 · PreprintDevelopmental Biology