Author

Ursula A. Matulonis

Brigham and Women's HospitalORCID 0000-0002-3103-6992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Elizabeth H. StoveriD· 2 shared Joyce F. LiuiD· 2 shared Aaron N. HataiD· 1 shared Adam G. PresseriD· 1 shared Alexander M. TsankoviD· 1 shared Anand G. PateliD· 1 shared Åsa KarlströmiD· 1 shared Asaf RotemiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Elizabeth H. StoverORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Targeting FGFR signaling overcomes therapeutic resistance and immune evasion in oncogenic PIK3CA-driven serous-like endometrial cancer

Xin Cheng, Y Zhang, Changli Qian, Erica M. Holdridge, Guruprasad Ananda, Tao Jiang, Jing Ni, Shaozhen Xie, Hao Gu, Renlei Ji, Elena V. Ivanova, Marisa R. Nucci, Zhe Wang, Kaifu Chen, Bose S. Kochupurakkal, , Jean J. Zhao

This study identifies FGFR signaling as a driver of resistance and immune evasion in PIK3CA-driven serous-like endometrial cancer and shows that dual FGFR/PI3K inhibition improves tumor control.

Nature Communications · May 4, 2026Peer-reviewedCancer Biology

Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance

Xingping Qin, Adam G. Presser, Lissah Johnson, Yusuke Matoba, Brendan Shay, Weiyi Xu, Jonathan Choiniere, Cameron Fraser, Filip Garbicz, Johan K. E. Spetz, Stacey J. Yu, Mary H.C. Florido, Francesca Picucci, Yang Yang, Ronny Drapkin, , Kristopher A. Sarosiek

bioRxiv · Jun 24, 2025 · PreprintCancer Biology

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

Michal Slyper, Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro, Christopher S. Smillie, Gabriela Smith-Rosario, Jingyi Wu, Danielle Ashley Dionne, Sébastien Vigneau, Judit Jané‐Valbuena, Timothy L. Tickle, Sara Napolitano, Mei-Ju Su, , Aviv Regev

The paper develops a toolbox for scRNA-Seq and snRNA-Seq of fresh and frozen human tumors, testing it across eight tumor types and optimizing protocols for different tissue characteristics.

Nature Medicine · May 1, 2020Peer-reviewedGenomics