Kia M. Barclay

Distinct contribution of autoreactive B cell Bruton's tyrosine kinase signaling to neuroinflammation

This study shows that deleting BTK in B cells reduces EAE severity by impairing autoreactive B cell functions, supporting BTK as a therapeutic target in MS.

Microglial plasticity governed by state-specific enhancer landscapes

This study identifies microglial subpopulations and shows their origin and transitions through transcriptomic and epigenomic analysis.

An inducible genetic tool for tracking and manipulating specific microglial states in development and disease

This paper develops an inducible genetic tool to study microglial states in development and disease, revealing their plasticity and functional roles.

Ontogenetic Oxycodone Exposure Affects Early-Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice

This study examines the effects of in utero and postnatal oxycodone exposure on mouse behavior and development, finding sex-dependent weight changes, altered vocalizations, and sensorimotor delays.