Claire E. McKellar

Sexually dimorphic neurons in the Drosophila whole-brain connectome

The paper identifies and analyzes sexually dimorphic neurons in the Drosophila brain using connectome data to understand their connectivity and functional roles in behavior.

A split-GAL4 driver line resource for Drosophila neuron types

The paper describes a collection of split-GAL4 driver lines for targeting specific neuron types in Drosophila, enabling functional and molecular studies.

Neuronal wiring diagram of an adult brain

The paper presents the first neuronal wiring diagram of a whole adult Drosophila brain, revealing synaptic connections and circuit mechanisms underlying sensorimotor behaviors.

A leaky integrate-and-fire computational model based on the connectome of the entire adult Drosophila brain reveals insights into sensorimotor processing

The paper creates a computational model of the Drosophila brain connectome to study sensorimotor processing and validates predictions through experiments.

Network Statistics of the Whole-Brain Connectome of Drosophila

The paper analyzes the network properties of the Drosophila whole-brain connectome, identifying rich club organization and signal integration/broadcasting neurons.

Comparative connectomics of the descending and ascending neurons of the Drosophila nervous system: stereotypy and sexual dimorphism

The paper provides a connectomic description of ascending and descending neurons in the Drosophila nervous system, revealing sexual dimorphism and motor-related circuits.

Neurotransmitter Classification from Electron Microscopy Images at Synaptic Sites in Drosophila Melanogaster

The paper uses artificial neural networks to classify neurotransmitters from electron microscopy images of Drosophila melanogaster synapses, achieving high accuracy and revealing ultrastructural differences.

From connectome to effectome: learning the causal interaction map of the fly brain

The paper introduces a method to learn a causal model of the fly brain using a connectome and optogenetic perturbation data, revealing that global brain dynamics arise from small, localized circuits.

Whole-brain annotation and multi-connectome cell typing quantifies circuit stereotypy in Drosophila

Annotating the 127,978-neuron FlyWire fly connectome yields 4,552 cell types, 3,094 cross-validated against the hemibrain; cell-type edges above 10 synapses or 1.1% of input recur over 90% across hemispheres.

Neural Network Organization for Courtship Song Feature Detection in Drosophila

The paper maps the auditory pathway in Drosophila, identifies new cell types, and reveals a network of neurons with continuous song mode preferences and non-hierarchical connectivity.

FlyWire: Online community for whole-brain connectomics

FlyWire enables collaborative proofreading of whole-brain connectomes through an online platform, demonstrating its utility in reconstructing and analyzing mechanosensory neuron circuits.

3D reconstruction of cell nuclei in a full Drosophila brain

The paper reconstructs 3D cell nuclei in a Drosophila brain, identifying over 133,000 nuclei, mostly neurons, and highlights differences in nuclear size and cell density across brain regions.

The Neural Basis for a Persistent Internal State in Drosophila Females

This study identifies pC1-Alpha neurons in Drosophila females that drive persistent behaviors through recurrent neural connectivity.

Simultaneous Activation Of Parallel Sensory Pathways Promotes A Grooming Sequence In Drosophila

The paper confirms a model where simultaneous activation of sensory pathways in Drosophila elicits a sequential grooming response through prioritized suppression.