Author

Persephone Borrow

University of OxfordORCID 0000-0002-3877-9780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Barton F. HaynesiD· 2 shared Simon BrackenridgeiD· 2 shared Andrew J. McMichael· 1 shared Anna E. KliszczakiD· 1 shared Annalisa NicastriiD· 1 shared Anthony T. PhaniD· 1 shared Anyway Brenda KapingidzaiD· 1 shared Benjamin DavisiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

Barton F. HaynesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Impact of RNA modification and IL-12 boosts on mRNA-LNP vaccine-elicited CD8+ T cell responses

Sampa Santra, Michelle A. Lifton, Benjamin Mildenberg, Georgeanna Morton, Han Nhat Tran, Laura L. Sutherland, Robert Parks, Whitney Edwards, Bette Korber, Anthony T. Phan, Christopher A. Hunter, Garima Dwivedi, Benjamin Davis, Justin Su, Mohamad‐Gabriel Alameh, , Barton F. Haynes

This study compares CD8+ T cell and antibody responses in non-human primates using different ratios of modified and unmodified mRNA-LNP vaccines with IL-12 boosting.

bioRxiv · Nov 1, 2026 · PreprintImmunology

HLA-E-VL9 antibodies enhance NK cell and CD8+ T cell cytotoxicity against HIV-infected CD4+ T cells

Joyce K Hwang, Daniel J. Marston, Marina Tuyishime, Hongbing Yang, Daniel Wrapp, Dapeng Li, Simon Brackenridge, McKenzie Frazier, Brianna Rhodes, Caitlin Harris, Max Quastel, Anyway Brenda Kapingidza, Anna E. Kliszczak, Jacob Gater, Persephone Borrow, , Mihai L. Azoitei

This study develops anti-HLA-E-VL9 antibodies that enhance NK and CD8+ T cell cytotoxicity against HIV-infected cells by blocking NKG2A/CD94 interactions and promoting ADCC.

bioRxiv · Jul 8, 2024 · PreprintImmunology

HLA binding of self-peptides is biased towards proteins with specific molecular functions

Vadim K Karnaukhov, Wayne Paes, Isaac B. Woodhouse, Thomas Partridge, Annalisa Nicastri, Simon Brackenridge, D. N. Scherbinin, Dmitriy M. Chudakov, Ivan V. Zvyagin, Nicola Ternette, Hashem Koohy, Persephone Borrow, Mikhail Shugay

The paper shows HLA alleles preferentially present peptides from proteins with specific molecular functions, linking these preferences to HLA allele differences and disease susceptibility.

bioRxiv · Feb 16, 2021 · PreprintBioinformatics