Roland Immler

Anchored for action: a dual role for integrin β1 in mast cell perivascular positioning and vasoactivity to license leukocyte recruitment

This study shows that integrin β1 is essential for mast cell positioning around arterioles and their vasoactive function, which are critical for leukocyte recruitment during inflammation.

Preimplantation factor (PIF) is an endogenous inhibitor of potassium channel KV1.3 regulating neutrophil function during pregnancy

The paper identifies PIF as a placenta-derived peptide that inhibits KV1.3 channels in neutrophils, altering their function during pregnancy.

Cytosolic S100A8/A9 promotes Ca2+ supply at LFA-1 adhesion clusters during neutrophil recruitment

The paper shows that cytosolic S100A8/A9 is essential for neutrophil adhesion under flow by regulating Ca2+ availability at LFA-1 adhesion clusters.

eATP/P2X7R axis drives nanoparticle induced neutrophil recruitment in the pulmonary microcirculation

This study identifies the eATP/P2X7R axis as a driver of nanoparticle-induced neutrophil recruitment in the pulmonary microcirculation using intravital microscopy in mice.