This paper constructs a CITE-seq-based atlas of mouse hematopoietic progenitors, identifying 28 progenitor stages across eight lineages and novel surface markers.

bioRxiv · Sep 12, 2026 · PreprintImmunology

CSF single-cell RNA sequencing reveals clonally expanded CD4+ stem cell-like memory T cells in GAD65-antibody associated neurological syndromes

Sumanta Barman, Saskia Jania Räuber, Katharina Eisenhut, Daniela Esser, Martijn M. VanDuijn, Madeleine Scharf, Marisol Herrera-Rivero, Paul Disse, Marius Jonas, Duygu Pul, Michael Heming, Louisa Müller‐Miny, Manuela Paunovic, Christine Strippel, Ebru Haholu, , cooperation with the EMC-AIE Study group

The paper uses single-cell RNA sequencing to identify clonally expanded CD4+ stem cell-like memory T cells in the CSF of anti-GAD65 AINS patients, suggesting their role in disease pathogenesis.

bioRxiv · May 18, 2025 · PreprintImmunology

In vitro characterisation and neurosteroid treatment of an N-Methyl-D-Aspartate receptor antibody-mediated seizure model

Sukhvir K. Wright, Richard Ewald Rosch, Max A Wilson, Manoj A. Upadhya, Divya Dhangar, Charlie Clarke-Bland, Tamara T. Wahid, Sumanta Barman, Norbert Goebels, Jakob Kreye, Harald Prüß, Leslie W. Jacobson, Danielle S. Bassett, Angela Carmen Vincent, Stuart Greenhill, Gavin L. Woodhall

This study develops an NMDAR-Ab-mediated rat seizure model and shows that reducing excitatory neurotransmission, not inhibitory, causes seizures, which can be mitigated by a neurosteroid.

bioRxiv · Dec 22, 2020 · PreprintNeuroscience