Ingrid Chamma

Dissecting the binding mechanisms of synaptic membrane adhesion complexes using a micropattern based cellular model

This study measures the binding kinetics of synaptic ligand-receptor interactions using a micropatterned cellular model and identifies differences in binding regimes between SynCAM1 and Nrx1β-Nlg1 complexes.

Engineering paralog-specific PSD-95 synthetic binders as potent and minimally invasive imaging probes

The paper develops synthetic binders specific to PSD-95 for imaging endogenous proteins with minimal impact on function and compatibility with super-resolution techniques.

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

The paper shows MDGAs delay excitatory synapse development by altering neuroligin behavior through fast diffusion and reduced mobility.