Author

Violaine André

University of OxfordORCID 0000-0002-1018-2472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

David J. H. F. KnappiD· 1 shared Edward M. JenkinsiD· 1 shared Hector Barbosa· 1 shared Hilary M. SheppardiD· 1 shared Huw Colin‐YorkiD· 1 shared Jake BurtoniD· 1 shared Jesús A. Siller‐FarfániD· 1 shared Jose Cabezas-CaballeroiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

David J. H. F. KnappORCID

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2 papers

Recent·Most cited

Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes

Jake Burton, Jesús A. Siller‐Farfán, Violaine André, Edward M. Jenkins, Michael I. Barton, Sofı́a Bustamante Eguiguren, Jose Cabezas-Caballero, Simon J. Davis, Thomas R. Weikl, P. Anton van der Merwe, Omer Dushek

The antigen sensitivity of CAR-T cells can be tuned to match the sensitivity of TCR-T cells by varying the relative extracellular size of CAR/antigen and CD2/CD58 complexes.

bioRxiv · Jan 6, 2025 · PreprintImmunology

Precise tuning of gene expression output levels in mammalian cells

Yale S. Michaels, Mike Bogetofte Barnkob, Hector Barbosa, Toni A. Baeumler, Mary Kay Thompson, Violaine André, Huw Colin‐York, Marco Fritzsche, Uzi Gileadi, Hilary M. Sheppard, David J. H. F. Knapp, Thomas A. Milne, Vincenzo Cerundolo, Tudor A. Fulga

This paper introduces miSFITs, synthetic microRNA response elements that allow precise control of gene expression levels in mammalian cells, showing their utility in modulating antigen expression in a mouse melanoma model.

Nature Communications · Feb 18, 2019Peer-reviewedSynthetic Biology