Author

Juan J Apiz Saab

University of ChicagoORCID 0000-0002-4799-9291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

Alexander MuiriD· 3 shared Adam C. SoloffiD· 1 shared Aidan R. ColeiD· 1 shared Akash KishoreiD· 1 shared Allison C. SharrowiD· 1 shared Althea Bock-HughesiD· 1 shared Amanda J. McFarlane· 1 shared Amandine AmalriciD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

Alexander MuirORCID

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3 papers

Recent·Most cited

Cancer BiologyEMBO ReportsPeer-reviewedJul 23, 2025

Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung

Declan Whyte, Sophie L Fisher, Christopher G J McKenzie…·Cassie J. Clarke

15 citationstop 3%

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivMar 10, 2025

Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis

Patrick B. Jonker, Mumina Sadullozoda, Guillaume Cognet…·Alexander Muir

The paper shows that arginine restriction in the tumor microenvironment limits lipid synthesis in pancreatic cancers, making them susceptible to polyunsaturated fatty acids via ferroptosis.

1 citation

humanmetabolomics

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Cancer BiologybioRxivPreprintFeb 8, 2025

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis

Raquel Buj, Aidan R. Cole, Jeff Danielson…·Katherine M. Aird

This study shows that zinc availability in the tumor microenvironment affects anti-PD1 therapy response in CDKN2A-low tumors through macrophage phagocytosis.

3 citations

mouseproteomics

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