Author

Roland E. van Dijk

Utrecht University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Onur BaşakiD· 2 shared Anja Moltke JørgenseniD· 1 shared Anneke MiedemaiD· 1 shared Astrid M. AlsemaiD· 1 shared Astrid WachteriD· 1 shared Bart J. L. EggeniD· 1 shared Danai RigaiD· 1 shared Daniëlle PosthumaiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Onur BaşakORCID

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3 papers

Recent·Most cited

Molecular Signatures and Cellular Diversity During Mouse Habenula Development

Lieke L. van de Haar, Danai Riga, Juliska E. Boer, Oxana Garritsen, Youri Adolfs, Thomas E. Sieburgh, Roland E. van Dijk, Kyoko Watanabe, Nicky C.H. van Kronenburg, Mark H. Broekhoven, Daniëlle Posthuma, Frank Julius Meye, Onur Başak, R. Jeroen Pasterkamp

This study identifies molecular signatures and cellular diversity during mouse habenula development using single-cell transcriptomics and links developmental subtypes to psychiatric disease.

Cell Reports · Jul 1, 2022Peer-reviewedDevelopmental Biology

Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue

Astrid M. Alsema, Qiong Jiang, Laura Kracht, Emma Gerrits, Marissa Lisa Dubbelaar, Anneke Miedema, Nieske Brouwer, Elly M. Hol, Jinte Middeldorp, Roland E. van Dijk, Maya E. Woodbury, Astrid Wachter, Hualin Simon Xi, Thomas Möller, Knut Biber, , Bart J. L. Eggen

The paper profiles microglia transcriptomes in AD donors and non-demented elderly using bulk and single-cell RNA sequencing, finding no significant differences in gene expression or subcluster composition.

Frontiers in Molecular Neuroscience · Oct 28, 2020Peer-reviewedNeuroscience

Single-cell analysis reveals cellular heterogeneity and molecular determinants of hypothalamic leptin-receptor cells

Nefeli Kakava-Georgiadou, Jeppe F. Severens, Anja Moltke Jørgensen, Iris Stoltenborg, Keith M. Garner, Mieneke C. M. Luijendijk, V. Drkelic, Roland E. van Dijk, Suzanne L. Dickson, Tune H. Pers, Onur Başak, Roger A.H. Adan

The paper uses scRNA-seq to analyze LepR cells in the hypothalamus, identifying eight neuronal clusters and 17 non-neuronal populations, and finds enrichment of obesity GWAS signals in multiple clusters.

bioRxiv · Jul 23, 2020 · PreprintNeuroscience